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Tri-Mix Injection
A compounded prescription injectable treatment for erectile dysfunction containing three active ingredients that work to increase blood flow to the penis.
- Produces reliable erection within 5–20 minutes
- Works independently of sexual arousal or nerve issues
- Custom compounded ratio tailored by your physician
- Ideal for men who do not respond to oral ED pills
Select Prescription Plan
Prescription required. Evaluated by licensed medical clinicians. If not approved, you are not charged.
About Tri-Mix
Tri-Mix is a compounded injectable medication containing three complementary active ingredients: papaverine, phentolamine, and alprostadil. It is injected directly into the penile tissue using a very fine needle, producing a reliable erection within minutes. Tri-Mix is typically considered when oral PDE5 inhibitors have not produced sufficient results.
What makes Tri-Mix different?
Tri-Mix acts locally on penile tissue rather than through systemic circulation, which is why it is effective for men with underlying vascular, neurological, or hormonal conditions that limit the effectiveness of oral treatments. The compounded formulation allows doses to be precisely titrated by your provider to your individual response.
Works when pills don't
Direct local action bypasses digestive absorption and vascular roadblocks.
Rapid onset in minutes
Produces firmness within 5–20 minutes without waiting hours.
Customized compound
Your clinician adjusts ingredient ratios specifically for your physiology.
Active Ingredients & Action
- Papaverine: Relaxes smooth muscle in penile tissue, improving blood inflow.
- Phentolamine: An alpha-blocker that reduces vascular resistance and supports sustained erection.
- Alprostadil: A prostaglandin E1 analogue that directly stimulates penile blood flow.
How to Use & Dosage Guidance
- Injected into the side of the penis using a micro-fine needle.
- Works rapidly within 5–20 minutes.
- Dose carefully titrated by your provider.
- Do not inject more than 3 times per week.
Important Safety Information
Tri-Mix Injection is a prescription medication. Common potential side effects may include Mild pain at injection site, Temporary bruising, Prolonged erection (seek urgent care if >4 hours), Tissue irritation with improper technique. Do not take if you have severe cardiovascular conditions or take nitrate medications. An individualized clinical assessment by a licensed healthcare professional is required before any prescription can be dispensed.
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